NEUROLOGY AND TRAUMA RESEARCH FOUNDATION
Preserving Memories for Life
The Neurology and Trauma Research Foundation (NTRF) is a nonprofit organization dedicated to preserving memory, protecting cognitive function, and improving lives through pioneering neuroscience research and therapeutic innovation.
Our mission is to advance novel therapeutics and diagnostics for neurological and central nervous system (CNS) disorders, including:
  • Concussions and traumatic brain injury (TBI)
  • Chronic traumatic encephalopathy (CTE)
  • Parkinson’s disease
  • Vascular dementia and other neurodegenerative disorders
  • Diseases associated with mitochondrial dysfunction
  • Autism Spectrum Disorder
Through scientific collaboration and clinical research, NTRF works to transform discoveries in neuroscience into safe and effective treatments that restore cognitive function and improve quality of life.
NTRF is a U.S. IRS 501(c)(3) non-profit organization | EIN: 93-3435428
Protecting Brain Health Through Science
NTRF is committed to advancing therapies that address the underlying biological causes of neurological disease.
Our work focuses on:
01
Translating scientific discoveries into clinical treatments
02
Supporting innovative therapeutics
03
Accelerating therapeutic clinical trials for neurological disorders
04
Improving access to treatments for underserved populations
Memory and cognition is essential to preserving human identity and quality of life.
Advancing Breakthrough Treatments for Brain Health
Novel therapeutics and diagnostics for neurological and central nervous system (CNS) disorders, including:
Traumatic Brain Injury (TBI) and Concussions
Diseases associated with mitochondrial dysfunction
Parkinson’s Disease
Chronic Traumatic Encephalopathy (CTE)
Vascular Dementia and other neurodegenerative disorders
Autism Spectrum Disorder
Why This Clinical Research Matters
Neurological injuries, neurodegenerative disorders, and neurodevelopmental conditions represent one of the fastest-growing health challenges worldwide.
Research has shown alarming statistics across the spectrum of neurological conditions:
Concussions trigger oxidative stress, inflammation, and neuronal dysfunction that can lead to long-term cognitive decline - similar mechanisms observed in other neurodevelopmental disorders.
Emerging research suggests shared pathophysiological mechanisms between traumatic brain injury and neurodegenerative disorders, including dysregulated immune responses, impaired cellular energy production, and chronic oxidative stress.
A significant percentage of former professional football players show evidence of chronic traumatic encephalopathy (CTE). Repeated head trauma is associated with increased risk of dementia and neurodegenerative diseases.
Autism spectrum disorder (ASD) now affects 1 in 36 children in the United States, with growing evidence linking oxidative stress, neuroinflammation, and mitochondrial dysfunction to its development and severity.
NTRF's research aims to intervene earlier in the disease process across multiple neurological conditions. By targeting the fundamental cellular mechanisms - oxidative stress, inflammation, and mitochondrial dysfunction—that underlie both traumatic brain injuries and neurodevelopmental disorders, our therapeutics have the potential to restore brain health, improve cognitive function, and enhance quality of life before irreversible damage occurs. This integrated approach recognizes that breakthrough treatments for one neurological condition may offer hope for many others.
Research Focus: Advancing the Science of Neuroprotection
NTRF supports research programs investigating therapeutic approaches that:
Address oxidative stress and inflammation in the brain
Restore mitochondrial function
Repair neuronal damage
Support neuroregeneration and synaptic plasticity
Improve cognitive recovery following brain injury
Our strategy prioritizes therapeutic candidates that:
Are supported by strong scientific evidence
Target multiple biological mechanisms involved in neurological disease
Address root causes of cellular dysfunction
Can reach patients more rapidly than traditional drug development pathways
Current Clinical Research:
The Jerry Kramer Neuro Studies™
The Jerry Kramer Neuro Studies™ are a series of clinical trials designed to investigate an innovative therapeutic candidate for treating concussions and traumatic brain injury.
The studies are to evaluate:
Safety and tolerability of the investigational therapy
Cognitive recovery following concussion
Reduction of oxidative stress in the brain
Improvement of neurological function
The clinical trial program is designed to address the growing global burden of neurotrauma, particularly among athletes, military personnel, and individuals exposed to repeated head injuries.
Investigational Therapeutic: XMR99B
XMR99B is a patented therapeutic compound designed to support neurological recovery following traumatic brain injury.
The compound is designed to:
Cross the blood–brain barrier
Stabilize neuronal membranes
Support mitochondrial repair
Reduce inflammation and oxidative stress
Promote neuronal regeneration and neurotransmitter balance
The Montagnier Studies™
The Montagnier Studies™ are a series of clinical trials designed to investigate an innovative therapeutic candidate for treating Autism Spectrum Disorder (ASD).
The studies are to evaluate:
Safety and tolerability of the investigational therapy
Improvement of neurological and behavioral function
Improvement in detoxification
Reduction of oxidative stress and inflammation in the brain
The clinical trial program is designed to address one of the root causes of a multifactorial family of complex diseases, one associated with over 70% of Autism Spectrum Disorder patients.
NTRF Welcomes Strategic Partnerships with:
Clinicians and researchers
Universities and medical institutions
Biotechnology companies
Investors and philanthropic partners
Partnership Opportunities include:
Collaborative clinical trials
Research sponsorship and funding
Strategic partnerships in neurotherapeutics development
Joint ventures in neurodevelopmental and neurotrauma research
Through scientific collaboration and clinical research, NTRF transforms discoveries in neuroscience into safe and effective treatments. The Jerry Kramer Neuro Studies build upon earlier clinical research demonstrating the study drug's ability to support cellular recovery processes and address the fundamental mechanisms underlying neurological disorders..
Together, we can accelerate the development of breakthrough treatments that:
  • Protect memory and cognition
  • Support brain health across the lifespan
  • Address autism, TBI, and neurodegenerative conditions
  • Restore cognitive function and improve quality of life
  • Join us in building the future of neurological care.
The Jerry Kramer Neuro Studies build upon earlier clinical research demonstrating the ability of study drug to support cellular recovery processes.
© The Neurology and Trauma Research Foundation™ All other trademarks including Jerry Kramer Neuro Studies™ Nuroxel™ are the intellectual property of Mito BioSciences and its affiliates. Preserving Memories for Life™ is a pending Trade Mark with the USPTO.
Join the Mission to Preserve Memories
NTRF is building the future of neurological therapeutics - and we need your support..
PARTNER WITH US
Collaborate on clinical trials and research programs
FUND RESEARCH
Support groundbreaking neuroscience that saves lives
JOIN OUR NETWORK
Connect with leading scientists, clinicians, and innovators
📧 contact@neurologytraumaresearch.org | 🌐 www.neurologytraumaresearch.org
Together, preserving memories for life.
The Neurology and Trauma Research Foundation is a U.S. IRS 501(c)(3) non-profit organization | EIN: 93-3435428